Intrauterine Insemination (IUI) – what it is and how it works

Short answer: Insemination (IUI) is a simpler fertility treatment where washed, concentrated sperm are inserted directly into the uterus around ovulation to increase the chance of fertilization. It is often used as a first step before IVF, for example, in cases of unexplained infertility, mildly reduced sperm quality, or when using donor sperm.

What is insemination?

During insemination, sperm are placed directly into the uterus using a thin catheter, instead of fertilization occurring through intercourse. The sperm are first washed and concentrated in the laboratory. The treatment is simpler and less invasive than IVF.

How it works

Sometimes hormones are given to stimulate ovulation or to control timing. Ovulation is monitored, and at the right time, the sperm are inserted – a quick and usually painless procedure. After that, one typically waits to see if pregnancy occurs.

Who is IUI suitable for?

IUI may be relevant for unexplained infertility, mildly reduced sperm quality, certain ovulation problems, or when using donor sperm (for example, for single individuals or same-sex couples).

IUI or IVF?

IUI is simpler and cheaper but has a lower chance per attempt than IVF. Often, IUI is tried first for a few cycles, and if unsuccessful, one proceeds to IVF. What is suitable is determined by the investigation.

Frequently asked questions

Does insemination hurt?
Usually not – most people experience it as a short and mild procedure, similar to a gynecological examination.

What is the chance of success?
The chance per attempt is lower than with IVF and depends, among other things, on age and cause. Your clinic can provide an individual assessment.

This article provides general information and does not constitute medical advice. Contact a fertility clinic for assistance.

Sources